Outlining the Complex Pathway of Mammalian Fe-S Cluster Biogenesis

Nunziata Maio, Tracey A. Rouault; Trends in Biochemical Sciences, 2020, doi:10.1016/j.tibs.2020.02.001.

Structural determinations of the architecture of the initial ISC biogenesis complex, comprising NFS1, ISD11, ACP, ISCU, and FXN, have shed light on the interactions that govern de novo ISC assembly.


Outlining the Complex Pathway of Mammalian Fe-S Cluster Biogenesis