Interactions of reactive sulfur species with metalloproteins

ndrea Domán, Éva Dóka, Dorottya Garai, Virág Bogdándi, György Balla, József Balla, Péter Nagy; Redox Biology, 2023, 102617, ISSN 2213-2317, doi:10.1016/j.redox.2023.102617. 

The current review summarizes the interactions of RSS with protein metal centers and their biological implications with special emphasis on mechanistic aspects, sulfide-mediated signaling, and pathophysiological consequences. A deeper understanding of the biological actions of reactive sulfur species on a molecular level is primordial in H2S-related drug development and the advancement of redox medicine.

Interactions of reactive sulfur species with metalloproteins