Monday, June 5, 2023

Amplifying gene expression with RNA-targeted therapeutics

Khorkova O, Stahl J, Joji A, Volmar CH, Wahlestedt C. Amplifying gene expression with RNA-targeted therapeutics. Nature reviews. Drug Discovery. 2023 May. DOI: 10.1038/s41573-023-00704-7. PMID: 37253858; PMCID: PMC10227815. 

This Review highlights emerging RNA-targeted therapeutics for gene activation, focusing on opportunities and challenges for translation to the clinic.