ALTERED ZINC TRANSPORT DISRUPTS MITOCHONDRIAL PROTEIN PROCESSING/IMPORT IN FRAGILE X-ASSOCIATED TREMOR/ATAXIA SYNDROME.

Hum Mol Genet. 2011 May 10. [Epub ahead of print]

Napoli E, Ross-Inta C, Wong S, Omanska-Klusek A, Barrow C, Iwahashi C, Garcia-Arocena D, Sakaguchi D, Berry-Kravis E, Hagerman R, Hagerman PJ, Giulivi C.
Source

Department of Molecular Biosciences, School of Veterinary Medicine.

Keywords: Fragile X-associated tremor/ataxia syndrome (FXTAS), common phenotypic traits shared by Friedreich's ataxia, gait ataxia, loss of coordination, iron homeostasis, mature frataxin protein expression, zinc, iron, desferrioxamine.