Effects of Erythropoietin on Frataxin Levels and Mitochondrial Function in Friedreich Ataxia - a Dose-Response Trial.

Cerebellum. 2011 May 20. [Epub ahead of print]

Nachbauer W, Hering S, Seifert M, Steinkellner H, Sturm B, Scheiber-Mojdehkar B, Reindl M, Strasak A, Poewe W, Weiss G, Boesch S.
Source
Department of Neurology, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.

Keywords: Friedreich ataxia (FRDA), frataxin, recombinant human erythropoietin (rhuEPO), dose-response interactions, single doses (5,000, 10,000 and 30,000 IU), serum erythropoietin levels, iron metabolism, mitochondrial function, ataxia rating did not reveal clinical improvement, ferritin decrease.