Thursday, November 17, 2011

Primary and Secondary Drug Screening Assays for Friedreich Ataxia.

J Biomol Screen. 2011 Nov 15. [Epub ahead of print]

Cotticelli MG, Rasmussen L, Kushner NL, McKellip S, Sosa MI, Manouvakhova A, Feng S, White EL, Maddry JA, Heemskerk J, Oldt RJ, Surrey LF, Ochs R, Wilson RB.

Keywords: Friedreich ataxia (FRDA), neuro- and cardiodegenerative disorder, frataxin, decreased ISC assembly, mitochondrial iron accumulation, increased oxidative stress, tetrazolium dye WST-1, compounds screen.