Mitochondrial quality control: a matter of life and death for neurons

The EMBO Journal (2012) 31, 1336 - 1349, doi:10.1038/emboj.2012.38

Elena I Rugarli 1,2 and Thomas Langer 2,3,4
1 Institute for Zoology, University of Cologne, Cologne, Germany
2 Center for Molecular Medicine (CMMC) and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany
3 Institute for Genetics, University of Cologne, Cologne, Germany
4 Max-Planck-Institute for Biology of Aging, Cologne, Germany

Keywords: mitochondria, mitochondrial fusion, mitophagy, mitochondrial proteases, neurodegeneration