The many faces of insulin-like peptide signalling in the brain

Nature Reviews Neuroscience 13, 225-239 (April 2012) | doi:10.1038/nrn3209

Ana M. Fernandez & Ignacio Torres-Alemán

Keywords: insulin-like peptides (ILPs), insulin, insulin-like growth factor 1 (IGF1) and IGF2, brain, regulate energy homeostasis.

Comment: The IGF-1 has been proposed as a possible FA treatment by several researchers, it have even performed a clinical trial proof of concept, the results has been inconclusive because of its short duration and small number of participants