363 Cardiac effect of high doses idebenone therapy compared to low doses in patients with friedreich ataxia

363 Cardiac effect of high doses idebenone therapy compared to low doses in patients with friedreich ataxia. D. Velasco Sanchez, J. Thérien, M. Vanasse, N. Dahdah, A. Fournier. Montréal, QuébecCanadian Journal of Cardiology
Volume 27, Issue 5, Supplement , Pages S192-S193, September 2011

Keywords: Heart involvement in Friedreich's ataxia (FRDA), progressive hypertrophic cardiomyopathy, idebenone, high dose idebenone (Hi-IDB), low dose of idebenone (Lo-IDB), paediatric FDRA patients, clinical and echocardiographic data -systolic and diastolic function, left ventricular wall thickness and mass index (LVMi), statistically significant LVMi reduction, improved mitral deceleration time with Hi-IDB.