TALE proteins induced the expression of the frataxin gene.

TALE proteins induced the expression of the frataxin gene. Prof. Jacques P Tremblay, Mr. Pierre Chapdelaine, Zoé Coulombe, and Joël Rousseau. Human Gene Therapy. -Not available-, ahead of print. doi:10.1089/hum.2012.034.

 The TALEFrat increased by 2 to 3 folds the frataxin gene expression and potentially could alleviate the symptoms of Friedreich ataxia.

Keywords: Tal effector proteins(TALE), transcription activator, expression of a gene, Friedreich ataxia (FRDA), frataxin, TALE genes (TALEFrat), VP16 peptides, mCherry reporter gene