Thursday, March 23, 2023

Dimorphic frataxin and its gene regulation by sex steroids in hamsters

Ramos L. (2023). Dimorphic frataxin and its gene regulation by sex steroids in hamsters. Molecular genetics and genomics : MGG, 10.1007/s00438-023-02004-6.  Advance online publication. doi:10.1007/s00438-023-02004-6 

 The mRNA expression results indicated that Harderian FXN may play a dynamic role in intracellular Fe of heme required for processing cytochromes and other hemeproteins, also suggesting that the moderate sexual dimorphism present in the HG and gonads could be regulated by androgens, while sexually dimorphic expression of FXN in the female pancreas may be controlled by sex steroids.