Thermodynamic Stabilization of Human Frataxin

Thermodynamic Stabilization of Human Frataxin. Reyes Núñez-Franco, Angel Torres-Mozas, Claudio D. Navo, Andreas Schedlbauer, Mikel Azkargorta, Ibon Iloro, Félix Elortza, Gabriel Ortega, Oscar Millet, Francesca Peccati, Gonzalo Jiménez-Osés. bioRxiv 2023.09.08.556816; doi:10.1101/2023.09.08.556816

This case-study highlights the power of our combined computational approach to generate optimized variants, adequate for protein-based therapeutics.

Thermodynamic Stabilization of Human Frataxin