Interferon gamma as a potential therapy for Friedreich ataxia

Interferon gamma as a potential therapy for Friedreich ataxia. B. Tomassini, G. Arcuri, S. Fortuni, C. Sandi, V. Ezzatizadeh, C. Casali, I. Condo, F. Malisan, S. Al-Mahdawi, M. Pook, R. Testi; Journal of the Neurological Sciences, Volume 333, Supplement 1, 15 October 2013, Page e474. http://dx.doi.org/10.1016/j.jns.2013.07.1686

Treatment with interferon gamma, a drug currently approved for pediatric indications, shows potential as a therapy for FRDA. A phase II clinical trial, aimed at assessing tolerability of interferon gamma and the ability of interferon gamma to elevate frataxin levels in FRDA patients, is currently underway