Substantia nigra hypoechogenicity is not related to Friedreich ataxia. M. Sierra, J. Infante, J. Berciano; Journal of the Neurological Sciences, Volume 333, Supplement 1, 15 October 2013, Pages e146-e147. http://dx.doi.org/10.1016/j.jns.2013.07.488
Our data do not support the notion that SN hypoechogenicity is related to FRDA itself, although it might be associated with RLS.