p53 directly regulates the transcription of the human frataxin gene and its lack of regulation in tumor cells decreases the utilization of mitochondrial iron

p53 directly regulates the transcription of the human frataxin gene and its lack of regulation in tumor cells decreases the utilization of mitochondrial iron. Rina Shimizu, Nguyen Ngoc Lan, Tran Tien Tai, Yuka Adachi, Asako Kawazoe, Anfeng Mu, Shigeru Taketani; Gene, Available online 23 August 2014, ISSN 0378-1119, http://dx.doi.org/10.1016/j.gene.2014.08.043.

Keywords: Frataxin; p53; Transcription; Heme biosynthesis; ALA; Cancerous cells