A Yeast/Drosophila Screen to Identify New Compounds Overcoming Frataxin Deficiency

Alexandra Seguin, Véronique Monnier, Amandine Palandri, Frédéric Bihel, Michael Rera, Martine Schmitt, Jean-Michel Camadro, Hervé Tricoire, and Emmanuel Lesuisse; Oxidative Medicine and Cellular Longevity, Volume 2015 (2015), Article ID 565140, 10 pages DOI: 10.1155/2015/565140

The unique complementarity of these two frataxin-deficient models, unicellular and multicellular, appears to be very efficient to select new compounds with improved selectivity, bringing significant perspectives towards improvements in FA therapy.

 A Yeast/Drosophila Screen to Identify New Compounds Overcoming Frataxin Deficiency