Neurofilament light chain as a potential biomarker of disease status in Friedreich ataxia

Alexandra Clay, Kristin M. Obrochta, Russell K. Soon Jr, Christopher B. Russell & David R. Lynch; Neurol (2020). doi:10.1007/s00415-020-09868-3

Because NfL is elevated in patients, but decreases with age and disease progression, our results suggest that age is the critical determinant of NfL in FRDA (rather than clinical or genetic severity).


Neurofilament light chain as a potential biomarker of disease status in Friedreich ataxia