Wednesday, July 15, 2009

Incision-dependent and error-free repair of (CAG)(n)/(CTG)(n) hairpins in human cell extracts

Nat Struct Mol Biol. 2009 Jul 13

Hou C, Chan NL, Gu L, Li GM.
Graduate Center for Toxicology and Markey Cancer Center, University of Kentucky College of Medicine, Lexington, Kentucky, USA.

Keywords: Expansion of CAG/CTG trinucleotide repeats, neurological disorders, Huntington's disease, proliferating cell nuclear antigen (PCNA), endonuclease activities, trinucleotide repeat instability.

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