Cell Therapy Instigates Neural Repair In Friedreich’s Ataxia Mice

RELIAWIRE, March 26, 2018; Author: Geoffrey Potjewyd; Regenerative Medicine & Neuroscience PhD student at the University of Manchester.

The group found that transplantation of bone marrow cells that express frataxin into the FRDA mice caused the upregulation of frataxin as well as a number of antioxidative proteins, as well as improving movement and coordination in the mice. The researchers also observed the reversal of FRDA disease pathology, along with integration of transplanted bone marrow cells into damaged nervous system tissue and transplanted cells contributing genetic material to neurons and myelinating Schwann cells.

Cell Therapy Instigates Neural Repair In Friedreich’s Ataxia Mice