UCLA Newsroom, Wileen Wong Kromhout December 17, 2009
Protein therapy — the delivery of healthy proteins directly into human cells to replace malfunctioning proteins — is considered one of the most direct and safe approaches for treating diseases. But its effectiveness has been limited by low delivery efficiency and the poor stability of proteins, which are frequently broken down and digested by cells' protease enzymes before they reach their intended target. read more
Thursday, June 17, 2010
Monday, June 14, 2010
More Discovered About The Composition Of Human Spinal Fluid
Medicalnewstoday, Article Date: 12 Jun 2010
A team of scientsts has sharply expanded scientific knowledge of the composition of human spinal fluid. The researchers have identified 2,630 proteins that reside in fluid that is considered "normal," a number nearly three times as great as the total number of proteins previously identified. Another striking finding was that more than half (56%) of the proteins were relatively unique to the spinal fluid and not found in blood. read more
A team of scientsts has sharply expanded scientific knowledge of the composition of human spinal fluid. The researchers have identified 2,630 proteins that reside in fluid that is considered "normal," a number nearly three times as great as the total number of proteins previously identified. Another striking finding was that more than half (56%) of the proteins were relatively unique to the spinal fluid and not found in blood. read more
Sunday, June 13, 2010
Longitudinal tracking of gait and balance impairments in cerebellar disease
Movement Disorders, Published Online: 11 Jun 2010, DOI 10.1002/mds.23169
Sussanne M. Morton, PhD, PT 1, Ya-Weng Tseng, PhD, PT 2, Kathleen M. Zackowski, PhD, OTR 3 4 5, Jaclyn R. Daline, PT, DPT 6, Amy J. Bastian, PhD, PT 3 4 5 *
1Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
2Department of Physical Therapy, Temple University, Philadelphia, Pennsylvania, USA
3Kennedy Krieger Institute, Baltimore, Maryland, USA
4Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
5Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
6Program in Physical Therapy, Washington University School of Medicine, St. Louis, Missouri, USA
Keywords: ICARS,cerebellum, walking, ataxia, clinical assessment, sensitivity
Sussanne M. Morton, PhD, PT 1, Ya-Weng Tseng, PhD, PT 2, Kathleen M. Zackowski, PhD, OTR 3 4 5, Jaclyn R. Daline, PT, DPT 6, Amy J. Bastian, PhD, PT 3 4 5 *
1Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
2Department of Physical Therapy, Temple University, Philadelphia, Pennsylvania, USA
3Kennedy Krieger Institute, Baltimore, Maryland, USA
4Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
5Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
6Program in Physical Therapy, Washington University School of Medicine, St. Louis, Missouri, USA
Keywords: ICARS,cerebellum, walking, ataxia, clinical assessment, sensitivity
Friday, June 11, 2010
Obstacles to Stem Cell Therapy Cleared
ScienceDaily (June 8, 2010) — Researchers at Lund University have come up with a new technique to prevent tumours developing in connection with stem cell transplantations. read more
Original paper: Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors. R. Sachdeva, M. E. Jonsson, J. Nelander, A. Kirkeby, C. Guibentif, B. Gentner, L. Naldini, A. Bjorklund, M. Parmar, J. Jakobsson. Proceedings of the National Academy of Sciences, 2010; DOI: 10.1073/pnas.1006568107
Original paper: Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors. R. Sachdeva, M. E. Jonsson, J. Nelander, A. Kirkeby, C. Guibentif, B. Gentner, L. Naldini, A. Bjorklund, M. Parmar, J. Jakobsson. Proceedings of the National Academy of Sciences, 2010; DOI: 10.1073/pnas.1006568107
Erythropoietin Activates Mitochondrial Biogenesis and Couples Red Cell Mass to Mitochondrial Mass in the Heart
Circulation Research. 2010;106:1722, doi: 10.1161/CIRCRESAHA.109.214353
From the Departments of Medicine (Pulmonary [M.S.C., C.-W.C., C.A.P.] and Cardiology [W.S.J.]), Anesthesiology (H.B.S., A.B., C.A.P.), and Pathology (C.A.P.), Duke University Medical Center Durham, NC. Present address for M.S.C.: Environmental Public Health Division, US Environmental Protection Agency, Chapel Hill, NC. Present address for C.-W.C.: Division of Chest Medicine, Department of Internal Medicine, Tri-Service General Hospital, Taipei, Taiwan. Present address for A.B.: Department of Virology and Immunology, Faculty of Medicine, King Khalid University, Abha, Saudi Arabia.
Wednesday, June 9, 2010
A Closer Look at Stem Cell Treatments
The International Society for Stem Cell Research (ISSCR) has launched this new Web site "A Closer Look at Stem Cell Treatments", it's aimed to patients, their families and doctors, it contains information that can be very useful to make decisions about the new promising stem cell treatments. The ISSCR urges individuals to be cautious and to learn the facts before making any decision.
"Una mirada cercana a los tratamientos con células madre",
La Sociedad Internacional para la Investigación con Células Madre (ISSCR) ha puesto en marcha este nuevo sitio Web "Una mirada cercana a los tratamientos con células madre", está dirigida a los pacientes, sus familias y los médicos, contiene información que puede ser muy útil para tomar decisiones acerca de los nuevos y prometedores tratamientos con células madre. La ISSCR insta a tener cuidado y estudiar los detalles antes de tomar cualquier decisión.
"Una mirada cercana a los tratamientos con células madre",
La Sociedad Internacional para la Investigación con Células Madre (ISSCR) ha puesto en marcha este nuevo sitio Web "Una mirada cercana a los tratamientos con células madre", está dirigida a los pacientes, sus familias y los médicos, contiene información que puede ser muy útil para tomar decisiones acerca de los nuevos y prometedores tratamientos con células madre. La ISSCR insta a tener cuidado y estudiar los detalles antes de tomar cualquier decisión.
Monday, June 7, 2010
Treatment of neurological scoliosis of more than 1008 by using a hybrid contstruct (pedicle screws plus universal clamps)
La Rosa G, Giglio G, Oggiano L.
Treatment of neurological scoliosis of more than 1008 by using a hybrid contstruct (pedicle screws plus universal clamps). Paper #F484. To be presented at the EFORT Congress 2010. June 2-5, 2010. Madrid.
Hybrid construct provides adequate correction of deformity in patients with neurological scoliosi.
Italian orthopaedists reported a low rate of complications when treating patients with high-grade neurological scoliosis using a hybrid construct that combined lumbar pedicle screws, Universal Clamps (Zimmer) and thoracic hooks...... read more
Treatment of neurological scoliosis of more than 1008 by using a hybrid contstruct (pedicle screws plus universal clamps). Paper #F484. To be presented at the EFORT Congress 2010. June 2-5, 2010. Madrid.
Hybrid construct provides adequate correction of deformity in patients with neurological scoliosi.
Italian orthopaedists reported a low rate of complications when treating patients with high-grade neurological scoliosis using a hybrid construct that combined lumbar pedicle screws, Universal Clamps (Zimmer) and thoracic hooks...... read more
Saturday, June 5, 2010
Frataxin and mitochondrial Fe-S cluster biogenesis.
The Journal of biological chemistry (3 June 2010)
Timothy L. Stemmler1, Emmanuel Lesuisse2, Debkumar Pain3, Andrew Dancis4.
Wayne State University School of Medicine, United States; CNRS-Universite Paris Diderot, France; UMDNJ, New Jersey Medical School, United States; 4 University of Pennsylvania, United States
Keyword: Friedreich's ataxia, neurodegenerative disease, frataxin, mitochondrial protein, Fe-S cluster, Isu, iron, cysteine desulfurase Nfs1.
FULL TEXT PDF
Timothy L. Stemmler1, Emmanuel Lesuisse2, Debkumar Pain3, Andrew Dancis4.
Wayne State University School of Medicine, United States; CNRS-Universite Paris Diderot, France; UMDNJ, New Jersey Medical School, United States; 4 University of Pennsylvania, United States
Keyword: Friedreich's ataxia, neurodegenerative disease, frataxin, mitochondrial protein, Fe-S cluster, Isu, iron, cysteine desulfurase Nfs1.
FULL TEXT PDF
Wednesday, June 2, 2010
Breakthrough In Stem Cell Culturing
Medical News Today, Article Date: 02 Jun 2010
For the first time, human embryonic stem cells have been cultured under chemically controlled conditions without the use of animal substances, which is essential for future clinical uses. The method has been developed by researchers at Karolinska Institutet and is presented in the journal Nature Biotechnology. read more
For the first time, human embryonic stem cells have been cultured under chemically controlled conditions without the use of animal substances, which is essential for future clinical uses. The method has been developed by researchers at Karolinska Institutet and is presented in the journal Nature Biotechnology. read more
Immune System Helps Transplanted Stem Cells Navigate in Central Nervous System
ScienceDaily (June 1, 2010) — By discovering how adult neural stem cells navigate to injury sites in the central nervous system, UC Irvine researchers have helped solve a puzzle in the creation of stem cell-based treatments: How do these cells know where to go?
Subscribe to:
Posts (Atom)
