Tuesday, June 25, 2013

Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitro models of the rat blood--brain barrier and blood-spinal cord barrier

Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitro models of the rat blood--brain barrier and blood-spinal cord barrier. P Marc Watson, Judy C Paterson, George Thom, Ulrika Ginman, Stefan Lundquist and Carl I Webster, BMC Neuroscience 2013, 14:59 doi:10.1186/1471-2202-14-59 Published: 18 June 2013

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"Interesting in vitro model to test if drugs can reach neurons, in Friedreich's ataxia it's a major handicap reach the neurons to improve the neurological symptoms"

Saturday, June 22, 2013

Osteopenia and osteoporosis in Friedreich's ataxia

Osteopenia and osteoporosis in Friedreich's ataxia. Nachbauer, W., Eigentler, A., Gasser, R., Poewe, W., Boesch, S.; Movement Disorders 2013;28 Suppl 1 :698

Keywords: osteoporosis, osteopenia, Friedreich ataxia (FRDA), demographic, clinical values, increased risk of fractures, osteodensitometry, wheelchair-bound patients.

Friday, June 21, 2013

Friedreich ataxia: metal dysmetabolism in dorsal root ganglia

Friedreich ataxia: metal dysmetabolism in dorsal root ganglia. Arnulf H Koeppen, Erik C Kuntzsch, Sarah T Bjork, R Liane Ramirez, Joseph E Mazurkiewicz and Paul J Feustel. Acta Neuropathologica Communications 2013, 1:26 doi:10.1186/2051-5960-1-26
Published: 19 June 2013

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Thursday, June 20, 2013

Mitochondrial Diseases of the Brain

Mitochondrial Diseases of the Brain. Rajnish K. Chaturvedi, M. Flint Beal. Free Radical Biology and Medicine, Volume 63, October 2013, Pages 1-29. http://dx.doi.org/10.1016/j.freeradbiomed.2013.03.018

Keywords: Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, Amyotrophic lateral sclerosis, Charcot-Marie-Tooth, Friedreich’s ataxia, Neurodegenerative diseases, Mitochondrial dysfunction, Creatine, Co-Q10, PGC-1α, Sirtuins, Free radicals.

Analysis of the visual system in Friedreich ataxia.

Analysis of the visual system in Friedreich ataxia. Seyer LA, Galetta K, Wilson J, Sakai R, Perlman S, Mathews K, Wilmot GR, Gomez CM, Ravina B, Zesiewicz T, Bushara KO, Subramony SH, Ashizawa T, Delatycki MB, Brocht A, Balcer LJ, Lynch DR. Journal of neurology : 2013 Jun 18 pg.

Keywords: optical coherence tomography (OCT), contrast letter acuity, GAA repeat length, highly correlated with neurological outcomes, markers of neurologic progression in FRDA.

Friday, June 14, 2013

The neuroprotective and neurorescue effects of carbamylated erythropoietin Fc fusion protein (CEPO-Fc) in a rat model of Parkinson’s disease

The neuroprotective and neurorescue effects of carbamylated erythropoietin Fc fusion protein (CEPO-Fc) in a rat model of Parkinson’s disease; Judith Thomas Tayra, Masahiro Kameda, Takao Yasuhara, Takashi Agari, Tomohito Kadota, Feifei Wang, Yoichiro Kikuchi, Hanbai Liang, Aiko Shinko, Takaaki Wakamori, Brigitta Vcelar,Brain Research, Volume 1502, 28 March 2013, Pages 55–70. http://dx.doi.org/10.1016/j.brainres.2013.01.042

Keywords: Carbamylated erythropoietin, Dopamine, Neuroprotection, Neurorescue, Parkinson’s disease

Brain-Computer Interfaces Make New Tasks As Simple As Waving A Hand

Brain-Computer Interfaces Make New Tasks As Simple As Waving A Hand. University of Washington. (2013, June 14). "Brain-Computer Interfaces Make New Tasks As Simple As Waving A Hand." Medical News Today

This technology could improve communication and daily life for a person who is paralyzed or has lost the ability to speak from a stroke or neurodegenerative disease.

Saturday, June 8, 2013

Friedreich’s and other hereditary ataxias in Greece: an 18-year perspective

Friedreich’s and other hereditary ataxias in Greece: an 18-year perspective Georgios Koutsis, Athina Kladi, Georgia Karadima, Henry Houlden, Nicholas W. Wood, Kyproula Christodoulou, Marios Panas. International Conference on Spinocerebellar degenerations. Brain and Spine Institute (ICM), Pitié-Salpêtrière Hospital, Paris (France), June 11-13, 2013. (ABSTRACTS SELECTED FOR PLATFORM PRESENTATIONS)

Genetic delineation of early onset cerebellar ataxia phenotypes in India through next generation sequencing

Genetic delineation of early onset cerebellar ataxia phenotypes in India through next generation sequencing Mohammed Faruq, Ankita Narang, Renu Kumari, Achal Kumar Sriavstava, Debasis Dash, Mitali Mukerji. International Conference on Spinocerebellar degenerations. Brain and Spine Institute (ICM), Pitié-Salpêtrière Hospital, Paris (France), June 11-13, 2013. (ABSTRACTS SELECTED FOR PLATFORM PRESENTATIONS)

Addressing Mitochondrial Function in a mouse model of Friedreich’s Ataxia (FRDA)

Addressing Mitochondrial Function in a mouse model of Friedreich’s Ataxia (FRDA) Rosella Abeti, Michael Parkinson, Chiranjeevi Sandi, Mark Pook, Andrey AY Abramov and Paola Giunti. International Conference on Spinocerebellar degenerations. Brain and Spine Institute (ICM), Pitié-Salpêtrière Hospital, Paris (France), June 11-13, 2013. (ABSTRACTS SELECTED FOR PLATFORM PRESENTATIONS)