PGC-1/β induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders

Human Molecular Genetics Advance Access originally published online on March 18, 2009
Human Molecular Genetics 2009 18(10):1805-1812; doi:10.1093/hmg/ddp093

PGC-1/β induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders

Sarika Srivastava1,,, Francisca Diaz1,, Luisa Iommarini1,3, Karine Aure4, Anne Lombes4 and Carlos T. Moraes1,2,*
1 Department of Neurology 2 Department of Cell Biology and Anatomy, University of Miami School of Medicine, 1095 NW 14th Terrace, Miami, FL 33136, USA 3 Dipartimento di Scienze Neurologiche, Università di Bologna, Bologna, Italy 4 Inserm 582; UPMC-Paris6; AP/HP, Paris F-75013, France
* To whom correspondence should be addressed. Tel: +1 3052435858; Fax: +1 3052433914; Email: cmoraes@med.miami.edu

Present address: Harvard Medical School, Boston, MA 02115, USA.