The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

Nature Cell Biology Published online: 17 May 2009 doi:10.1038/ncb1881

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

Angel Herrero-Mendez1, Angeles Almeida1,2, Emilio Fernández1, Carolina Maestre1,2, Salvador Moncada3 & Juan P. Bolaños1

Departamento de Bioquimica y Biologia Molecular, Universidad de Salamanca, Instituto de Neurociencias de Castilla y Leon, 37007 Salamanca, Spain.
Unidad de Investigacion, Hospital Universitario de Salamanca, Instituto de Estudios de Ciencias de la Salud de Castilla y Leon, 37007 Salamanca, Spain.
Wolfson Institute for Biomedical Research, University College London, Gower Street, London WC1E 6BT, UK.
Correspondence to: Juan P. Bolaños1 e-mail: jbolanos@usal.es
Correspondence to: Salvador Moncada3 e-mail: s.moncada@ucl.ac.uk