Oligomeric yeast frataxin drives assembly of core machinery for mitochondrial iron-sulfur cluster synthesis.

J Biol Chem. 2009 Jun 2.

Oligomeric yeast frataxin drives assembly of core machinery for mitochondrial iron-sulfur cluster synthesis.

Li H, Gakh O, Smith DY 4th, Isaya G.

Mayo Clinic, College of Medicine, United States.

Mitochondrial biosynthesis of iron-sulfur clusters (ISC)(1) is a vital process involving the delivery of elemental iron and sulfur to a scaffold protein .....

Keywords: iron-sulfur clusters, iron, sulfur, Yfh1, Nfs1-Isd11, Isu1, oligomerization, oxidation, mechanism, mitochondrial ISC synthesis..