Thursday, July 9, 2009

Large-Scale Expansions of Friedreich's Ataxia GAA Repeats in Yeast

MolecularCell, Volume 35, Issue 1, 10 July 2009, Pages 82-92

Alexander A. Shishkin1, Irina Voineagu1, Robert Matera1, Nicole Cherng1, Brook T. Chernet1, Maria M. Krasilnikova2, Vidhya Narayanan3, Kirill S. Lobachev3 and Sergei M. Mirkin1, ,
1Department of Biology, Tufts University, Medford, MA 02155, USA
2Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA
3School of Biology and Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332
Received 22 August 2008; revised 7 January 2009; accepted 18 June 2009. Published: July 9, 2009. Available online 9 July 2009.

Keywords: DNA repeats , GAA repeats, Friedreich's ataxia, chimeric URA3 gene, rates of expansions of GAA repeats.

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