Thursday, September 3, 2009

AAV9-mediated erythropoietin gene delivery into the brain protects nigral dopaminergic neurons in a rat model of Parkinson's disease

Gene Therapy, advance online publication 3 September 2009; doi: 10.1038/gt.2009.113

Y-Q Xue1,7, B-F Ma1,7, L-R Zhao1,2,3, J B Tatom4, B Li2, L-X Jiang5, R L Klein3,4 and W-M Duan1,3,6
1Department of Cellular Biology and Anatomy, Louisiana State University Health Sciences Center, Shreveport, LA, USA
2Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, LA, USA
3Gene Therapy Program, Louisiana State University Health Sciences Center, Shreveport, LA, USA
4Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, USA
5Vector Gene Technology Company LTD, Beijing, PR China
6Department of Anatomy and Neurobiology, Capital Medical University, Beijing, PR China
Correspondence: Dr W-M Duan, Department of Cellular Biology & Anatomy, LSU Health Sciences Center in Shreveport, 1501 Kings Highway, Shreveport, LA 71130, USA. E-mail: wduan@lsuhsc.edu
7These authors contributed equally to this work.
Received 17 March 2009; Revised 3 August 2009; Accepted 5 August 2009; Published online 3 September 2009.

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