A Periplasmic Reducing System Protects Single Cysteine Residues from Oxidation

(Related to the previous post, the source paper of the previus news)

Science 20 November 2009, Vol. 326. no. 5956, pp. 1109 - 1111, DOI: 10.1126/science.1179557
Matthieu Depuydt,1 Stephen E. Leonard,2 Didier Vertommen,1 Katleen Denoncin,1 Pierre Morsomme,3 Khadija Wahni,4,5 Joris Messens,4,5 Kate S. Carroll,2 Jean-François Collet1,*

de Duve Institute, Université catholique de Louvain, B-1200 Brussels, Belgium.
2 Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109–1048, USA.
3 Institut des Sciences de la Vie, Université catholique de Louvain, B-1348 Louvain-la-Neuve, Belgium.
4 Department of Molecular and Cellular Interactions, Vlaams Instituut voor Biotechnologie (VIB), Vrije Universiteit Brussel, B-1050 Brussels, Belgium.
5 Structural Biology Brussels, Vrije Universiteit Brussel, B-1050 Brussels, Belgium.

Keywords:  thiol group, cysteine,  disulfide bonds, oxidation,  sulfenic acids, sulfonic acids,  DsbG, DsbC,  thioredoxin-related proteins.