Tuesday, December 29, 2009

In Vivo Fluorescent Detection of Fe-S Clusters Coordinated by Human GRX2

Kevin G. Hoff124,Stephanie J. Culler14Peter Q. Nguyen2Ryan M. McGuire3Jonathan J. Silberg23, and Christina D. Smolke1
1 Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 E. California Boulevard, Mail Code 210-41, Pasadena, CA 91125, USA
2 Department of Biochemistry and Cell Biology, Rice University, 6100 Main Street, MS 140, Houston, TX 77005, USA
3 Department of Bioengineering, Rice University, 6100 Main Street, MS 140, Houston, TX 77005, USA

Keywords: Fe-S cluster biosynthesis, fluorescent approach, 2Fe2S clusters, Venus fluorescent protein, glutaredoxin 2 (GRX2), ISCU, NFS1. 

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