Mechanisms of brain iron transport: insight into neurodegeneration and CNS disorders

Eric Mills‌1, Xian-ping Dong‌1, Fudi Wang‌2 & Haoxing Xu‌1†
1Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 3089 Natural Science Building (Kraus), 830 North University, Ann Arbor, MI 48109, USA. haoxingx@umich.edu
2Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, PR China
 
Keywords: iron, copper, zinc, manganese, cobalt, iron-transport mechanisms in the CNS,  neurodegeneration ,CNS iron homeostasis, blood–brain barrier, novel therapeutic targets.