Saturday, July 31, 2010

Current and emerging treatment options in the management of Friedreich ataxia

Neuropsychiatric Disease and Treatment, Published Date July 2010 , Volume 2010:6 Pages 491 - 499

Michelangelo Mancuso, Daniele Orsucci, Anna Choub, Gabriele Siciliano
Department of Neuroscience, Neurological Clinic, University of Pisa, Pisa, Italy

Keywords: Friedreich ataxia (FRDA), Oxidative damage, mitochondria, antioxidant protection, idebenone, cardiac hypertrophy, frataxin gene transcription, iron-chelating therapies, erythropoietin, histone deacetylase inhibitors, gene-based strategies.

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