The Friedreich’s Ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals

Biochem. J. (2010) Immediate Publication, doi:10.1042/BJ20101116

René Thierbach, Gunnar Drewes, Markus Fußer, Anja Voigt, Doreen Kuhlow, Urte Blume, Tim J Schulz, Carina Reiche, Hansruedi Glatt, Bernd Epe, Pablo Steinberg and Michael Ristow

Department of Human Nutrition, University of Jena, Jena 07743, Germany. 

 

Keywords:  DNA repair mechanisms,  iron-sulphur-clusters (ISCs),  frataxin, Friedreich’s Ataxia,  cancer, 8-oxoguanine glycosylase.

 

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