Tuesday, April 19, 2011

A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress

BMC Systems Biology 2011, 5:51doi:10.1186/1752-0509-5-51

Fiona Achcar, Jean-Michel Camadro and Denis Mestivier

Interesting tool, could be helpful to understand better the role of frataxin in the iron homeostasis in Friedreich's ataxia. It could also provide some light to try to explain the great individual differences between genotype - phenotype.

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