Neurodegeneration in friedreich's ataxia is associated with a mixed activation pattern of the brain. A fMRI study.

Hum Brain Mapp. 2011 Jun 14. doi: 10.1002/hbm.21319. [Epub ahead of print]

Ginestroni A, Diciotti S, Cecchi P, Pesaresi I, Tessa C, Giannelli M, Nave RD, Salvatore E, Salvi F, Dotti MT, Piacentini S, Soricelli A, Cosottini M, De Stefano N, Mascalchi M.
Department of Clinical Physiopathology, Radiodiagnostic Section, University of Florence, Florence, Italy.

Keywords: Friedreich's ataxia (FRDA), neurodegeneration, spinal cord, brain, MR Imaging (fMRI), left primary sensory-motor cortex, right cerebellum, left thalamus, right dorsolateral prefrontal cortex, globus pallidus, anterior cingulum, globus pallidus, regional neuronal damage, compensatory significance.