Importance of Iron Chelation in Free Radical-Induced Oxidative Stress and Human Disease.

Curr Pharm Des. 2011 Sep 9,

Jomova K, Valko M.
Faculty of Chemical and Food Technology, Slovak Technical University, Bratislava, Slovakia.

Keywords: Iron, redox active metal, hemochromatosis, Alzheimer's disease, Parkinson's disease, Huntington's disease, Friedreich's ataxia, neurological disorders, cancer, Fanconi anemia, stroke, ageing, Fenton reaction, reactive oxygen species (ROS), iron-designed chelators.