Determination of Idebenone in Plasma by HPLC with Post -Column Fluorescence Derivatization using 2-Cyanoacetamide

Chem Pharm Bull, Regular Article, Analytical Chemistry

Yukio NOHARA a, Junko SUZUKI b, Yoji YAMAZAKI a, Hiroaki KUBO a.
a Faculty of Pharmacy, Iwaki Meisei University, Iwaki, Fukushima 970-8551, Japan
b School of Pharmacy, Kitasato University, Minato-ku, Tokyo 108-8641, Japan

Keywords: Idebenone, Friedreich’s ataxia, 2-cyanoacetamide, fluorescence, HPLC with post-column fluorescence derivatization, human blood plasma, finger prick.