The role of mitochondria in cellular iron-sulfur protein biogenesis and iron metabolism.

The role of mitochondria in cellular iron-sulfur protein biogenesis and iron metabolism. Lill R, Hoffmann B, Molik S, Pierik AJ, Rietzschel N, Stehling O, Uzarska MA, Webert H, Wilbrecht C, Mühlenhoff U.Biochim Biophys Acta. 2012 May 15.

 Keywords: Mitochondria, iron metabolism, synthesize heme, assemble iron-sulfur (Fe/S) proteins, cellular iron regulation, mitochondrial Fe/S cluster (ISC), cysteine desulfurase complex Nfs1-Isd11, ferredoxin-ferredoxin reductase, frataxin, scaffold protein Isu1, Hsp70 chaperone, glutaredoxin Grx5.

This article is part of a Special Issue entitled: Cell Biology of Metals.