Genome-wide Screen Identifies Pathways that Govern GAA/TTC Repeat Fragility and Expansions in Dividing and Nondividing Yeast Cells

Genome-wide Screen Identifies Pathways that Govern GAA/TTC Repeat Fragility and Expansions in Dividing and Nondividing Yeast Cells; Yu Zhang, Alexander A. Shishkin, Yuri Nishida, Dana Marcinkowski-Desmond, Natalie Saini, Kirill V. Volkov, Sergei M. Mirkin, Kirill S. Lobachev; Molecular Cell, Available online 6 September 2012, http://dx.doi.org/10.1016/j.molcel.2012.08.002

Keywords: Triplex structure-forming GAA/TTC repeats, gene inactivation, Friedreich’s ataxia, chromosomal fragile sites, chromosomal rearrangements, DNA replication.