Wednesday, December 12, 2012

Extranuclear Localization of SIRT1 and PGC-1α: An Insight into Possible Roles in Diseases Associated with Mitochondrial Dysfunction

Extranuclear Localization of SIRT1 and PGC-1α: An Insight into Possible Roles in Diseases Associated with Mitochondrial Dysfunction . Aquilano, K.; Baldelli, S.; Pagliei, B.; R. Ciriolo, M.; Current Molecular Medicine, Volume 13, Number 1, January 2013 , pp. 140-154(15). DOI: http://dx.doi.org/10.2174/156652413804486241

Keywords: Biogenesis, cellular metabolism, cytoplasm, mitochondria, mitochondrial diseases, transcriptional regulation, SIRT1, PGC-1α, neurodegenerative disorders, myopathies,Type II diabetes mellitus.