Tuesday, November 19, 2013

'Grammar' Plays Key Role in Activating Genes

'Grammar' Plays Key Role in Activating Genes. genes. ScienceDaily. Retrieved November 19, 2013, from http://www.sciencedaily.com­ /releases/2013/08/130812170336.htm

Researchers have probed deep into the cell's genome, beyond the basic genetic code, to begin learning the "grammar" that helps determine whether or not a gene gets switched on to make the protein it encodes.


Journal Reference:
Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model. Robin P Smith, Leila Taher, Rupali P Patwardhan, Mee J Kim, Fumitaka Inoue, Jay Shendure, Ivan Ovcharenko, Nadav Ahituv. Nature Genetics, 2013; DOI: 10.1038/ng.2713