Histone deacetylases (HDACs) and brain function

Histone deacetylases (HDACs) and brain function. Claude-Henry Volmar, Claes Wahlestedt, Neuroepigenetics, Available online 18 November 2014, ISSN 2214-7845, http://dx.doi.org/10.1016/j.nepig.2014.10.002.

Very little work has been done regarding the role of HDACs in neurologic disorders; however, a few studies show great promise. HDACs have been proposed as a target against the autosomal recessive neurodegenerative disorder Friedreich ataxia (FRDA)