Grant Alert: Elucidating the molecular basis of gene silencing by an ORC-HP1 interaction and their contribution to human health disorders

Grant Alert: Elucidating the molecular basis of gene silencing by an ORC-HP1 interaction and their contribution to human health disorders. Christian Speck (Principal Investigator), Till Bartke (Co-Investigator), Richard J Festenstein (Co-Investigator); Source: RCUK Grant #BBM0037601, Organisation: Imperial College London (BBSRC award)

Misregulation of 'heterochromatin' and HP1 is involved in several diseases, including epigenetic diseases such as Friedreich's Ataxia or Facioscapulohumeral muscular dystrophy.