DNA Topological and Epigenetic Regulation in Neurodevelopment and Disorders

DNA TOPOLOGICAL AND EPIGENETIC REGULATION IN NEURODEVELOPMENT AND DISORDERS . NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE, Project Number: 1K99NS091508-01, Project Leader: TEE, WEE WE, NEW YORK UNIVERSITY SCHOOL OF MEDICINE

PUBLIC HEALTH RELEVANCE: The goal of this project is to gain a mechanistic perspective on the roles of DNA topology and epigenetic regulation in neurodevelopment, and their implications in human neuropsychiatric disorders such as autism, and neurodegenerative diseases such as Freidreich's ataxia.