Transcription blockage by stable H-DNA analogs in vitro

Transcription blockage by stable H-DNA analogs in vitro. Shristi Pandey, Anna M. Ogloblina, Boris P. Belotserkovskii, Nina G. Dolinnaya, Marianna G. Yakubovskaya, Sergei M. Mirkin and Philip C. Hanawalt, Nucl. Acids Res. (2015) doi: 10.1093/nar/gkv622 First published online: June 22, 2015

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Formation of H-DNA has been implicated in transcription blockage by expanded (GAA)n repeats responsible for the human genetic disease Friedreich's ataxia