Stable isotopes and LC–MS for monitoring metabolic disturbances in Friedreich's ataxia platelets

Andrew J Worth, Sankha S Basu, Eric C Deutsch, Wei-Ting Hwang, Nathaniel W Snyder, David R Lynch, and Ian A Blair, Bioanalysis, Vol. 7, No. 15 , Pages 1843-1855 (doi: 10.4155/bio.15.118)

Platelets can be used as a surrogate tissue for in vivo biomarker studies to monitor new therapeutic approaches for the treatment of FRDA.


 Stable isotopes and LC–MS for monitoring metabolic disturbances in Friedreich's ataxia platelets