CNS Drug Delivery: Beyond the Spinal Cord

Recently the intrathecal administration has been proposed as part of a hopeful therapy for FA (Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich’s ataxia). This paper shows (in laboratory animals) the feasibility of the use of intrathecal administration to reach efficiently the dorsal root ganglia.

This presentation explains the current state of the art in other neurological diseases in which it is required reach the CNS.

Mission: Improve outcomes for epileptic patients who don’t respond to conventional treatments by administering reformulated, micro-doses of anti-epileptic drugs directly to the brain.

 CNS Drug Delivery: Beyond the Spinal Cord.pptx (5 MB, 3 downloads so far)