Oxidative Stress and altered lipid metabolism in Friedreich ataxia

Jordi Tamarit, Èlia Obis, Joaquim Ros, Free Radical Biology and Medicine, Available online 11 June 2016, ISSN 0891-5849, doi: 10.1016/j.freeradbiomed.2016.06.007.

Lipid metabolism is compromised in FA and therefore is emerging as a new potential therapeutic target. Current approaches are also meant to restore mitochondrial function, improve energy metabolism and decrease oxidative stress. Ongoing clinical trials will reveal the potential of these therapeutic strategies to attenuate disease progression.


 Oxidative Stress and altered lipid metabolism in Friedreich ataxia