CN Project OPUS10: “Role of microRNAs in regulation iron metabolism in Friedreich's ataxia”

biotechnologia.pl; Prof. Włodzimierz Krzyżosiak, Institute of Bioorganic Chemistry PAS, Polish Academy of Sciences.(2017-01-02)

The goals of this project are to define changes in the expression and activity of microRNAs in FRDA, and analyze how these abnormalities affect the activity of genes which are responsible for the localization and amount of iron in neuronal and heart cells of patients with Friedreich’s ataxia. We will define relationship between miRNA molecules and iron availability. We will also uncover the pattern of detectable microRNA molecules that is specific to FRDA.


 CN Project OPUS10: “Role of microRNAs in regulation iron metabolism in Friedreich's ataxia”