Emergence of breath testing as a new non-invasive diagnostic modality for neurodegenerative diseases

N. Siva Subramaniam, C.S. Bawden, H. Waldvogel, R.M.L. Faull, G.S. Howarth, R.G. Snell, , Brain Research, Available online 22 April 2018, ISSN 0006-8993, doi:10.1016/j.brainres.2018.04.017.

Neurodegenerative diseases (NDDs) are incapacitating disorders that result in progressive motor and cognitive impairment. These disease include Alzheimer’s disease the most common cause of dementia, frontotemporal dementia, amyotrophic lateral sclerosis, dementia with Lewy bodies, Parkinson’s, Huntington’s, Friedreich’s ataxia, and prion disease.
The use of breath testing, as a means of monitoring neurodegenerative disease onset and progression, has the potential to have a significant impact on augmenting the diagnosis of NDDs as the approach is non-invasive, relatively cost effective and straight forward to implement. This review highlights key features of current diagnostic methods utilised to identif.

Emergence of breath testing as a new non-invasive diagnostic modality for neurodegenerative diseases