Heart disease in Friedreich’s ataxia

Hanson E, Sheldon M, Pacheco B, Alkubeysi M, Raizada V.; World J Cardiol. Jan 26, 2019; 11(1): 1-12 Published online Jan 26, 2019. doi: 10.4330/wjc.v11.i1.1

The present review discusses the pathogenesis, clinical manifestations, and spectrum of cardiac disease in Friedreich’s Ataxia, and introduces gene-targeted and pathology-specific therapies, in addition to the screening guidelines that should be used to monitor cardiac disease in this mitochondrial disorder.

 Heart disease in Friedreich’s ataxia