Cerebellum and cognition in Friedreich ataxia: a voxel-based morphometry and volumetric MRI study

Sirio Cocozza, Te*resa Costabile, Giuseppe Pontillo, Maria Lieto, Camilla Russo, I Leonardo Radice,Chiara Pane, Alessandro Filla, Arturo Brunetti, Francesco Saccà; J Neurol (2019). doi:10.1007/s00415-019-09582-9

With two different image analysis techniques, we confirmed the presence of cerebellar volume loss in FRDA, mainly affecting the posterior lobe. In particular, Lobule IX atrophy correlated with worse visuo-spatial abilities, further expanding our knowledge about the physiopathology of cognitive impairment in FRDA.



Cerebellum and cognition in Friedreich ataxia: a voxel-based morphometry and volumetric MRI study